Animal use
Research
In vivo response to polypropylene following implantation in animal models: a review of biocompatibility
In 2017, the Medicines and Healthcare products Regulatory Agency (MHRA) conducted a review of papers into the reaction of polpropylene implants in animals. Animals cant talk of pain or loss of sex life – different endpoints in research – so is not useful. Additionally, it is not a thorough look at all of the evidence – known as a randomised controlled trial – so is low-quality evidence.
International Urogynecology Journal 28(2): 171-180. February 2017.
Use of a novel silk mesh for ventral midline hernioplasty in a mare
Mesh hernioplasty is the treatment of choice for large ventral midline hernias in horses to allow potential return to normal function. However, based on the literature, complication rates following mesh hernioplasty using synthetic, non-absorbable mesh are as high 60%, with mortality rates up to 50% following repair in large horses (heavier than 450kg). This report described the use of a novel bioresorbable silk mesh for repair of a large ventral midline incisional hernia in a 600kg horse – and suggested it potentially provides significant benefits over traditional non-resorbable mesh.
BMC Veterinary Research 11: 58. March 2015.
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